Quality Level
reaction suitability
core: nickel, reaction type: Cross Couplings, reagent type: catalyst
parameter
temperature sensitive
mp
60 °C (dec.) (lit.)
storage temp.
−20°C
SMILES string
[Ni].C1CC=CCCC=C1.C2CC=CCCC=C2
InChI
1S/2C8H12.Ni/c2*1-2-4-6-8-7-5-3-1;/h2*1-2,7-8H,3-6H2;/b2*2-1-,8-7-;
InChI key
JRTIUDXYIUKIIE-KZUMESAESA-N
Application
- 氧化加成反应
作为下列反应的催化剂：
- 酮与氯代芳烃的非对称α-芳基化和杂芳基化
- 交叉偶联反应
- 烯丙基醛在二氧化碳气氛中的区域选择性和立体选择性羧化/环化
- 均相炔醇的甲基羧化
- 立体选择性硼环化酮-二烯偶联
- 苯甲酰胺与内部炔烃的环加成反应
signalword
Danger
hcodes
Hazard Classifications
Carc. 2 - Flam. Sol. 1 - Skin Sens. 1 - STOT RE 1
target_organs
Lungs
存储类别
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
商品
Nickel complexes catalyze various synthetic reactions like oxidative addition, C-H activation, and cross-coupling.
Csp2- and Csp-hybridized coupling reactions are established catalytic approaches. However, multi-step Csp3- and Csp2-coupling reactions of boronic acids and related derivatives are still limited by ineffective two-electron transmetalation reactions.
Effective Csp2- and Csp-hybridized coupling reactions established for catalysis, expanding to multi-step Csp3-coupling.