P8139
佛波醇12-十四酸酯13-乙酸酯
≥99% (TLC), film or powder, PKC activator
别名:
12-O-十四烷酰基佛波醇13-乙酸酯, 4β,9α,12β,13α,20-五羟基噻吩-1,6-二烯-3-酮12-十四烷酸酯13-乙酸酯, PMA, TPA
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产品名称
佛波醇12-十四酸酯13-乙酸酯, ≥99% (TLC), film or powder
Quality Level
assay
≥99% (TLC)
form
film or powder
solubility
DMSO: soluble, ethanol: soluble (Dissolve in water-miscible organic solvent prior to preparing aqueous solutions.)
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)C(C=C(CO)C[C@@]3(O)C2C=C(C)C3=O)C4C(C)(C)[C@]14OC(C)=O
InChI
1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30-,32-,34-,35-,36-/m1/s1
InChI key
PHEDXBVPIONUQT-RGYGYFBISA-N
General description
Application
- 诱导THP-1单核细胞向巨噬细胞分化。
- 刺激外周血淋巴细胞增殖。
- 刺激HL-60细胞来源中性粒细胞样细胞，诱导呼吸爆发，增强超弱光子辐射(ultra-weak photon emission)发生。
- 联合离子霉素钙盐刺激T细胞活化。
- 刺激各种细胞，包括脾脏细胞、静止淋巴细胞和胚胎胸腺细胞。
- 激活细胞中的蛋白激酶C(PKC)。
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Danger
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Carc. 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
商品
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
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