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208922 CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem

The CaMKII Inhibitor, CK59, also referenced under CAS 140651-18-9, controls the biological activity of CaMKII. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59

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208922
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
140651-18-9C₂₁H₃₇N₇O₃

Products

Catalogue NumberPackaging Qty/Pack
208922-5MGCN 玻璃瓶 5 mg
Description
OverviewA cell-permeable Olomoucine (Cat. Nos. 495620 & 495624) analog that acts as a CaMKII inhibitor (IC50 <10 µM) and inhibits insulin-stimulated glucose uptake (IC50 ≤5 µM) and GLUT4 membrane translocation (IC50 = 100 µM) in 3T3-L1 adipocytes.
Catalogue Number208922
Brand Family Calbiochem®
Synonyms2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59
References
ReferencesKonstantopoulos, N., et al. 2007. Endocrinology, 148, 374.
Product Information
CAS number140651-18-9
FormYellow semi-solid
Hill FormulaC₂₁H₃₇N₇O₃
Chemical formulaC₂₁H₃₇N₇O₃
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
208922-5MGCN 04055977219104

Documentation

CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem Certificates of Analysis

TitleLot Number
208922

References

Reference overview
Konstantopoulos, N., et al. 2007. Endocrinology, 148, 374.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-February-2014 JSW
Synonyms2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59
DescriptionA cell-permeable Olomoucine (Cat. Nos. 495620 & 495624) analog that acts as a CaMKII inhibitor (IC50 <10 µM) and inhibits insulin-stimulated glucose uptake (IC50 ≤5 µM) and GLUT4 membrane translocation (IC50 = 100 µM) in 3T3-L1 adipocytes.
FormYellow semi-solid
Intert gas (Yes/No) Packaged under inert gas
CAS number140651-18-9
Chemical formulaC₂₁H₃₇N₇O₃
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (10 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesKonstantopoulos, N., et al. 2007. Endocrinology, 148, 374.