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852008 Fmoc-Cys(Trt)-OH

Fmoc-Cys(Trt)-OH Novabiochem®. CAS 103213-32-7, molar mass 585.72 g/mol.

Fmoc-Cys(Trt)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 103213-32-7 Molar Mass: 585.73 g/mol Hill Formula: C₇H₃₁NO₄S
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
103213-32-7C₇H₃₁NO₄S585.73 g/mol

Products

Catalogue NumberPackaging Qty/Pack
8.52008.0025 塑膠瓶 25 g
8.52008.0100 塑膠瓶 100 g
8.52008.0500 塑膠瓶 500 g
Description
Catalogue Number852008
Replaces04-12-1018
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-S-trityl-L-cysteine
Background InformationThe standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP®, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.

The product number for this product was previously 04-12-1018.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number103213-32-7
Hill FormulaC₇H₃₁NO₄S
Molar Mass585.73 g/mol
HS Code2930 90 19
Structure formula ImageStructure formula Image
Quality LevelMQ400
Applications
ApplicationFmoc-Cys(Trt)-OH Novabiochem®. CAS 103213-32-7, molar mass 585.72 g/mol.
Biological Information
Physicochemical Information
Melting Point164 - 175 °C
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 3 highly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -15°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to off white
Appearance of substance (visual)powder
Color index (0,5 M in DMF)≤ 150 Hazen
Identity (IR)passes test
Enantiomeric purity≥ 99.5 % (a/a)
Purity (HPLC)≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC)≤ 0.1 % (a/a)
Fmoc-ß-Ala-Cys (Trt) -OH (HPLC)≤ 0.1 % (a/a)
Fmoc-Cys(Trt)-Cys(Trt)-OH (HPLC)≤ 0.1 % (a/a)
Fmoc-Cys-OH (HPLC)≤ 0.1 % (a/a)
Assay free amino acid (HPLC)≤ 0.2 %
Purity (TLC(011A))≥ 98 %
Purity (TLC(0811))≥ 98 %
Solubility (1 mmole in 2 ml DMF)clearly soluble
Assay (acidimetric)≥ 98.0 %
Water (K. F.)≤ 2.0 %
Ethyl acetate (HS-GC)≤ 0.5 %
Acetate (IC)≤ 0.02 %
For TLC-Systems see our General Catalog
Global Trade Item Number
Catalogue Number GTIN
8.52008.0025 04027269084783
8.52008.0100 04027269084790
8.52008.0500 04027269179182

Documentation

Fmoc-Cys(Trt)-OH MSDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] S. N. McCurdy (1989) Pept. Res., 2, 147.
  • [2] T. Kaiser, et al. (1996) Tetrahedron Lett., 37, 1187.
  • [3] Y. X. Han, et al. (1997) J. Org. Chem., 62, 4307.
  • [4] Y. N. Angell (2002) J. Peptide Res., 5, 292.