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539572 Serine/Threonine Kinase Inhibitor Set - Calbiochem

539572
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539572-1SETCN
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      玻璃瓶 1 set
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      Description
      OverviewA convenient set that offers several highly selective serine/threonine kinase inhibitors. Set contains 250 µg of protein kinase C inhibitor, Bisindolylmaleimide I (Cat. No. 203290); 1 mg of protein kinase A inhibitor, H-89, Dihydrochloride (Cat. No. 371963); 1 mg of PKG inhibitor, Protein Kinase G Inhibitor (Cat. No. 370654); 1 mg of MLCK inhibitor, ML-7 (Cat. No. 475880); 1 mg of CaM kinase II inhibitor, KN-93 (Cat. No. 422708); and 100 µg of the broad range Serine/Threonine Kinase inhibitor, Staurosporine (Cat. No. 569397). Supplied with a data sheet.
      Catalogue Number539572
      Brand Family Calbiochem®
      Application Data
      References
      ReferencesMartiny, G., et al. 1993. J. Biol. Chem. 268, 9194.
      Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
      Chijiwa, T., et al. 1990. J. Biol. Chem. 265, 5267.
      Simu, M., et al. 1991. Biochem. Biophys. Res. Commun. 181, 968.
      Saitoh, M., et al. J. Biol. Chem. 262, 7796.
      Glass, D.B., et al. 1983. Biochem. J. 213, 159.
      Seynaeve, C.M., et al. 1994. Mol. Pharmacol. 45, 1207.
      Meyer, T., et al. 1989. Int. J. Cancer 43, 851.
      Product Information
      FormSolid
      Hygroscopic Hygroscopic
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKA
      Secondary targetPKC, MLCK, Cam kinase II, PKG
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 23/25-36/37/38-45-63

      Toxic by inhalation and if swallowed.
      Irritating to eyes, respiratory system and skin.
      May cause cancer.
      Possible risk of harm to the unborn child.
      S PhraseS: 22-36/37/39-45-53

      Do not breathe dust.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Avoid exposure - obtain special instructions before use.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Multiple Toxicity Values, refer to MSDS
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions of each inhibitor are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Serine/Threonine Kinase Inhibitor Set - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      Serine/Threonine Kinase Inhibitor Set - Calbiochem Certificates of Analysis

      TitleLot Number
      539572

      References

      Reference overview
      Martiny, G., et al. 1993. J. Biol. Chem. 268, 9194.
      Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
      Chijiwa, T., et al. 1990. J. Biol. Chem. 265, 5267.
      Simu, M., et al. 1991. Biochem. Biophys. Res. Commun. 181, 968.
      Saitoh, M., et al. J. Biol. Chem. 262, 7796.
      Glass, D.B., et al. 1983. Biochem. J. 213, 159.
      Seynaeve, C.M., et al. 1994. Mol. Pharmacol. 45, 1207.
      Meyer, T., et al. 1989. Int. J. Cancer 43, 851.

      Brochure

      Title
      Protein Kinase Assay and Detection Kits Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-September-2007 JSW
      Application Data
      DescriptionA convenient set that offers several highly selective serine/threonine kinase inhibitors. Kinases play an important role in numerous signaling cascades. Highly selective protein kinase inhibitors are useful for dissecting these cascades to determine which specific kinases are involved in producing particular biological effects. The Serine/Threonine Kinase Inhibitor Set contains the following highly selective serine/ threonine kinase inhibitors in one convenient set:

      • Bisindolylmaleimide I (Cat. No. 203290), 250 µg
      • H-89, Dihydrochloride (Cat. No. 371963), 1 mg
      • KN-93 (Cat. No. 422708), 1 mg
      • ML-7 (Cat. No. 475880), 1 mg
      • Protein Kinase G Inhibitor (Cat. No. 370654), 1 mg
      • Staurosporine (Cat. No. 569397), 100 µg
      FormSolid
      SolubilityH₂O (1 mg/ml; Protein Kinase G Inhibitor)
      DMSO (1 mg/ml; all other inhibitors)
      Storage -20°C
      Hygroscopic
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions of each inhibitor are stable for up to 3 months at -20°C.
      Toxicity Multiple Toxicity Values, refer to MSDS
      ReferencesMartiny, G., et al. 1993. J. Biol. Chem. 268, 9194.
      Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
      Chijiwa, T., et al. 1990. J. Biol. Chem. 265, 5267.
      Simu, M., et al. 1991. Biochem. Biophys. Res. Commun. 181, 968.
      Saitoh, M., et al. J. Biol. Chem. 262, 7796.
      Glass, D.B., et al. 1983. Biochem. J. 213, 159.
      Seynaeve, C.M., et al. 1994. Mol. Pharmacol. 45, 1207.
      Meyer, T., et al. 1989. Int. J. Cancer 43, 851.