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Merck

COL1A1

collagen, type I, alpha 1

Sinónimos:
OI4
Especie:
ID UniProtKB:
ID del gen:
  • Human(1277) Summary: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
  • Mouse(12842) collagen, type I, alpha 1
  • Rat(29393) collagen, type I, alpha 1
  • domestic guinea pig(100733209) collagen, type I, alpha 1
  • chicken(395532) collagen, type I, alpha 1
  • domestic cat(101092216) collagen, type I, alpha 1
  • dog(403651) collagen, type I, alpha 1
  • sheep(443483) collagen, type I, alpha 1
  • Goat(100860828) collagen, type I, alpha 1
  • cow(282187) collagen, type I, alpha 1
  • Horse(100033877) collagen, type I, alpha 1
  • Domestic Rabbit(100008952) collagen, type I, alpha 1
  • naked mole-rat(101703193) collagen, type I, alpha 1

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-Collagen, Type I antibody produced in mouse, clone COL-1, ascites fluid,
Reactividad de especies
bovine, deer, human, pig, rabbit, rat
Aplicación
ELISA
dot blot

immunohistochemistry
Anti-Collagen Type I antibody, Mouse monoclonal, clone COL-1, purified from hybridoma cell culture,
Reactividad de especies
bovine, deer, human, pig, rat
Aplicación
ELISA
dot blot

immunohistochemistry

western blot
Anticuerpo anti-colágeno tipo I de ratón, Chemicon®, from rabbit,
Reactividad de especies
mouse
Aplicación
ELISA
immunohistochemistry

radioimmunoassay

western blot
Anti-Procollagen Type I Antibody, NT, clone M-58, culture supernatant, clone M-58, Chemicon®,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Collagen Type I Antibody, Chemicon®, from goat,
Reactividad de especies
bovine, human
Aplicación
ELISA
dot blot

immunocytochemistry

immunohistochemistry

western blot

Proteins

Product Number
Descripción
Especie
Colágeno, tipo I solution from rat tail, BioReagent, suitable for cell culture, sterile-filtered,
Especie
rat
Colágeno tipo I, cola de rata, 100 mg, solution, BioReagent, suitable for cell culture,
Especie
rat
Collagen from calf skin, Bornstein and Traub Type I, solid, BioReagent, suitable for cell culture,
Especie
cow
Colágeno from rat tail, Bornstein and Traub Type I, powder, BioReagent, suitable for cell culture,
Especie
rat
Rat Tail Collagen Coating Solution (20 ML), Type I, 50 μg/mL, solution, BioReagent, suitable for cell culture,
Especie
rat

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Col1a1,
Especie
mouse
MISSION® esiRNA, targeting human COL1A1,
Especie
human