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Merck

ENSA

endosulfine alpha

Sinónimos:
ARPP-19e
Especie:
ID UniProtKB:
ID del gen:
  • Human(2029) Summary: The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(56205) endosulfine alpha
  • Rat(60334) endosulfine alpha
  • naked mole-rat(101725556) endosulfine alpha
  • chicken(425073) endosulfine alpha
  • sheep(101107055) endosulfine alpha
  • domestic guinea pig(100714626) endosulfine alpha
  • cow(281142) endosulfine alpha
  • dog(475837) endosulfine alpha
  • domestic cat(101085485) endosulfine alpha

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-ENSA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-ENSA antibody produced in mouse, clone 1H7, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Ensa,
Especie
mouse
MISSION® esiRNA, targeting human ENSA,
Especie
human