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Merck

FGFRL1

fibroblast growth factor receptor-like 1

Sinónimos:
FGFR5, FHFR
Especie:
ID UniProtKB:
ID del gen:
  • Human(53834) Summary: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(116701) fibroblast growth factor receptor-like 1
  • Rat(360903) fibroblast growth factor receptor-like 1
  • chicken(395107) fibroblast growth factor receptor-like 1
  • domestic cat(101095654) fibroblast growth factor receptor-like 1
  • cow(532327) fibroblast growth factor receptor-like 1
  • domestic guinea pig(100720221) fibroblast growth factor receptor-like 1
  • dog(488865) fibroblast growth factor receptor-like 1
  • dog(100505382) fibroblast growth factor receptor-like 1
  • naked mole-rat(101724061) fibroblast growth factor receptor-like 1

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-FGFRL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Fgfrl1,
Especie
mouse
MISSION® esiRNA, targeting human FGFRL1,
Especie
human