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Merck

ING3

inhibitor of growth family, member 3

Sinónimos:
Eaf4, ING2, MEAF4, p47ING3
Especie:
ID UniProtKB:
ID del gen:
  • Human(54556) Summary: The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(71777) inhibitor of growth family, member 3
  • Rat(312154) inhibitor of growth family, member 3
  • domestic guinea pig(100721269) inhibitor of growth family, member 3
  • sheep(101102722) inhibitor of growth family, member 3
  • cow(513000) inhibitor of growth family, member 3
  • dog(475299) inhibitor of growth family, member 3
  • Zebrafish(393911) inhibitor of growth family, member 3
  • naked mole-rat(101711218) inhibitor of growth family, member 3
  • domestic cat(101089592) inhibitor of growth family, member 3
  • chicken(417762) inhibitor of growth family, member 3
  • Horse(100056220) inhibitor of growth family, member 3
  • fruit fly(32853) CG6632 gene product from transcript CG6632-RA

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-ING3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-ING3 antibody produced in mouse, clone 2C4, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

western blot
Anti-ING3 Antibody, clone 2A2, clone 2A2, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-ING3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human ING3,
Especie
human
MISSION® esiRNA, targeting mouse Ing3,
Especie
mouse