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Merck

ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

Sinónimos:
CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Especie:
ID UniProtKB:
ID del gen:
  • Human(3684) Summary: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(16409) integrin alpha M
  • Rat(25021) integrin, alpha M
  • Horse(100064803) integrin, alpha M (complement component 3 receptor 3 subunit)
  • dog(489928) integrin, alpha M (complement component 3 receptor 3 subunit)
  • sheep(443217) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic guinea pig(100135561) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic cat(101087957) integrin, alpha M (complement component 3 receptor 3 subunit)
  • cow(407124) integrin, alpha M (complement component 3 receptor 3 subunit)
  • naked mole-rat(101719288) integrin, alpha M (complement component 3 receptor 3 subunit)
  • Domestic Rabbit(100351865) integrin, alpha M (complement component 3 receptor 3 subunit)

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ELISA

Product Number
Descripción
Especie
Human Integrin alpha-M ELISA, for serum, plasma and cell culture supernatants,
Especie
human

Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-Integrin αM [CD11b] Antibody, clone OX-42, clone OX-42, Chemicon®, from mouse,
Reactividad de especies
rat
Aplicación
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Milli-Mark® Anti-CD11B-PE Antibody, clone 2LPM19c, clone 2LPM19c, Milli-Mark®, from mouse,
Reactividad de especies
human
Aplicación
flow cytometry
Monoclonal Anti-CD11b−FITC antibody produced in mouse, clone ICRF44, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
flow cytometry
Anti-Integrin αM [CD11b] Antibody, clone OX-42, FITC conjugated, clone OX-42, Chemicon®, from mouse,
Reactividad de especies
rat
Aplicación
flow cytometry
immunohistochemistry
Anti-CD11b/CD18 Antibody, clone mAb107, clone mAb107, from mouse,
Reactividad de especies
human, nonhuman primates
Aplicación
dot blot
flow cytometry

immunohistochemistry

inhibition assay

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Itgam,
Especie
mouse
MISSION® esiRNA, targeting human ITGAM,
Especie
human