KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
Sinónimos:
CD309, FLK1, VEGFR, VEGFR2
Especie:
Human KDR (3791), Mouse Kdr (16542), Rat Kdr (25589), chicken KDR (395323), Zebrafish kdr (554230), Thale Cress KDR (839585), dog KDR (482154), Goat KDR (100860836), cow KDR (407170), Horse KDR (100033959) ...Más
ID UniProtKB:
ID del gen:
- Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
- Mouse(16542) kinase insert domain protein receptor
- Rat(25589) kinase insert domain receptor
- chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Thale Cress(839585) basic helix-loop-helix protein KIDARI
- dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
- cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
- sheep(443087) vascular endothelial growth factor receptor-2
- naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
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ELISA
Antibodies
Product Number
Descripción
Reactividad de especies
Aplicación
Anti-phospho-VEGFR2 (pTyr1175) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-VEGFR2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 antibody produced in mouse, clone KDR-1, ascites fluid,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
immunohistochemistry
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 (KDR) antibody produced in mouse, clone 260.4, KDR-2, ascites fluid,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-VEGFR2/Flk-1/KDR (Tyr1054) Antibody, Upstate®, from rabbit,
Reactividad de especies
danio, bovine, chicken, horse, human, mouse, primate, rat, zebrafish
Aplicación
western blot
Small Molecule - Inhibitor
Product Number
Descripción
Especie
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Especie
human
Proteins
Product Number
Descripción
Especie
KDR Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.,
for use in Kinase Assays.,
Especie
human
VEGF Receptor-2 (Flk-1, KDR)/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Especie
human