MAP2K1
mitogen-activated protein kinase kinase 1
Sinónimos:
CFC3, MAPKK1, MEK1, MKK1, PRKMK1
Especie:
Human MAP2K1 (5604), Mouse Map2k1 (26395), Rat Map2k1 (170851), domestic guinea pig Map2k1 (100712888), dog MAP2K1 (478347), Horse MAP2K1 (100065996), domestic cat MAP2K1 (101081387), chicken MAP2K1 (415549), naked mole-rat Map2k1 (101715628), cow MAP2K1 (533199) ...Más
ID UniProtKB:
ID del gen:
- Human(5604) Summary: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
- Mouse(26395) mitogen-activated protein kinase kinase 1
- Rat(170851) mitogen activated protein kinase kinase 1
- domestic guinea pig(100712888) mitogen-activated protein kinase kinase 1
- dog(478347) mitogen-activated protein kinase kinase 1
- Horse(100065996) mitogen-activated protein kinase kinase 1
- domestic cat(101081387) mitogen-activated protein kinase kinase 1
- chicken(415549) mitogen-activated protein kinase kinase 1
- naked mole-rat(101715628) mitogen-activated protein kinase kinase 1
- cow(533199) mitogen-activated protein kinase kinase 1
- Domestic Rabbit(100009316) mitogen-activated protein kinase kinase 1
- sheep(101123635) mitogen-activated protein kinase kinase 1
- Zebrafish(406728) mitogen-activated protein kinase kinase 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Descripción
Especie
Phospho-Mek (pSer217 / 221) ELISA Kit, for detection of phospho-mek (pSer217 / 221) in human, mouse or rat cell and tissue lysates,
Especie
human
Phospho-Mek (pSer217 / 221) and pan-Mek ELISA Kit, for detection of phospho-mek (pSer217 / 221) and pan-mek in human, mouse or rat cell and tissue lysates,
Especie
human
Antibodies
Product Number
Descripción
Reactividad de especies
Aplicación
Anti-MEK1 Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot
western blot
Anti-phospho-MEK1 (Ser218/222)/MEK2 (Ser222/226) Antibody, rabbit monoclonal, Upstate®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-phospho-MEK1 (Thr292) Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-MEK1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-MAP2K1 antibody produced in mouse, clone 1B5, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
western blot
Small Molecule - Inhibitor
Product Number
Descripción
Especie
U0126, U0126 is a elective inhibitor of MEK-1 and MEK-2; weak inhibitor of PKC, Raf, ERK, JNK, MEKK, MKK-3, MKK-4/SEK, MKK-6, Abl, Cdk2 and Cdk4.,
Especie
human
Proteins
Product Number
Descripción
Especie
Proteína MEK1, inactiva, 50 g, Unactive, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
Especie
human
MEK1 Protein, active, 10 µg, Active, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
Especie
human
MEK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
mouse