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Merck

MCM8

minichromosome maintenance complex component 8

Sinónimos:
C20orf154, dJ967N21.5
Especie:
ID UniProtKB:
ID del gen:
  • Human(84515) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(66634) minichromosome maintenance deficient 8 (S. cerevisiae)
  • Rat(296178) minichromosome maintenance complex component 8
  • domestic cat(101088566) minichromosome maintenance complex component 8
  • Horse(100065561) minichromosome maintenance complex component 8
  • cow(507507) minichromosome maintenance complex component 8
  • domestic guinea pig(100734936) minichromosome maintenance complex component 8
  • chicken(421314) minichromosome maintenance complex component 8
  • Domestic Rabbit(100337967) minichromosome maintenance complex component 8
  • dog(477163) minichromosome maintenance complex component 8
  • Thale Cress(820123) minichromosome maintenance 8
  • sheep(101116498) minichromosome maintenance complex component 8
  • naked mole-rat(101719798) minichromosome maintenance complex component 8

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-MCM8 Antibody, clone 2D4, ,
Reactividad de especies
human, mouse
Aplicación
ChIP
electron microscopy

immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-MCM8 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
Anti-MCM8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-MCM8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Mcm8,
Especie
mouse
MISSION® esiRNA, targeting human MCM8,
Especie
human