MMP25
matrix metallopeptidase 25
Sinónimos:
MMP-25, MMP20, MMP20A, MMPL1, MT-MMP 6, MT-MMP6, MT6-MMP, MT6MMP, MTMMP6
Especie:
Human MMP25 (64386), Mouse Mmp25 (240047), Rat Mmp25 (302963), sheep MMP25 (101120293), domestic cat MMP25 (101097941), naked mole-rat Mmp25 (101698825), dog MMP25 (490046), domestic guinea pig Mmp25 (100715085), cow MMP25 (531092)
ID UniProtKB:
ID del gen:
- Human(64386) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq, Jul 2008]
- Mouse(240047) matrix metallopeptidase 25
- Rat(302963) matrix metallopeptidase 25
- sheep(101120293) matrix metallopeptidase 25
- domestic cat(101097941) matrix metallopeptidase 25
- naked mole-rat(101698825) matrix metallopeptidase 25
- dog(490046) matrix metallopeptidase 25
- domestic guinea pig(100715085) matrix metallopeptidase 25
- cow(531092) matrix metallopeptidase 25
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Descripción
Reactividad de especies
Aplicación
Anti-MMP25 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-MMP25 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
ELISA
western blot
western blot