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Merck

NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Sinónimos:
NF-ATC, NFAT2, NFATc
Especie:
ID UniProtKB:
ID del gen:
  • Human(4772) Summary: The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013]
  • Mouse(18018) nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
  • Rat(100361818) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • Zebrafish(568315) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • dog(483925) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • Domestic Rabbit(100352378) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • domestic guinea pig(100730044) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • cow(511224) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • sheep(101108097) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • naked mole-rat(101697946) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • Horse(100065378) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • chicken(420815) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • domestic cat(101101259) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

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Small Molecule - Antagonist

Product Number
Descripción
Especie
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Especie
human, rat, mouse

Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-NFATC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-NFATC1 (ab1) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-NFATc1 Antibody, clone 1O16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
ELISA
affinity binding assay

immunocytochemistry

immunohistochemistry

western blot
Anti-NFAT2 Antibody, clone 4I9P10, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
western blot

Small Molecule - Inhibitor

Product Number
Descripción
Especie
NFAT Inhibitor, >96% (HPLC), solid,
Especie
mouse, human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Especie
human, rat, mouse

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Nfatc1,
Especie
mouse
MISSION® esiRNA, targeting human NFATC1,
Especie
human