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Merck

NPHP3

nephronophthisis 3 (adolescent)

Sinónimos:
MKS7, NPH3, RHPD
Especie:
ID UniProtKB:
ID del gen:
  • Human(27031) Summary: This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene. [provided by RefSeq, Feb 2011]
  • Mouse(74025) nephronophthisis 3 (adolescent)
  • Rat(363126) nephronophthisis 3 (adolescent)
  • dog(485665) nephronophthisis 3 (adolescent)
  • chicken(420690) nephronophthisis 3 (adolescent)
  • Zebrafish(562601) nephronophthisis 3
  • Horse(100064940) nephronophthisis 3 (adolescent)
  • naked mole-rat(101713364) nephronophthisis 3 (adolescent)
  • domestic guinea pig(100720089) nephronophthisis 3 (adolescent)
  • cow(507522) nephronophthisis 3 (adolescent)
  • sheep(101118406) nephronophthisis 3 (adolescent)
  • domestic cat(101090135) nephronophthisis 3 (adolescent)

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-NPHP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
ANTI-NPHP3 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Nphp3,
Especie
mouse
MISSION® esiRNA, targeting human NPHP3, NPHP3-ACAD11,
Especie
human
MISSION® esiRNA, targeting human ACAD11, NPHP3-ACAD11 (1),
Especie
human
MISSION® esiRNA, targeting human ACAD11, NPHP3-ACAD11 (2),
Especie
human