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Merck

OAS2

2'-5'-oligoadenylate synthetase 2, 69/71kDa

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(4939) Summary: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(246728) 2'-5' oligoadenylate synthetase 2
  • Rat(363938) 2'-5' oligoadenylate synthetase 2
  • domestic guinea pig(100722402) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
  • naked mole-rat(101698818) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
  • dog(611051) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
  • Horse(791250) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
  • cow(529660) 2'-5'-oligoadenylate synthetase 2, 69/71kDa
  • sheep(101109915) 2'-5'-oligoadenylate synthetase 2, 69/71kDa

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-OAS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-OAS2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-OAS2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, pig
Aplicación
western blot

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting human OAS2,
Especie
human