PPARA
peroxisome proliferator-activated receptor alpha
Sinónimos:
NR1C1, PPAR, PPARalpha, hPPAR
Especie:
Human PPARA (5465), Mouse Ppara (19013), Rat Ppara (25747), domestic guinea pig Ppara (100135604), chicken PPARA (374120), naked mole-rat Ppara (101725514), Domestic Rabbit PPARA (100009308), Goat PPARA (100861393), sheep PPARA (100190976), dog PPARA (403654) ...Más
ID UniProtKB:
ID del gen:
- Human(5465) Summary: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
- Mouse(19013) peroxisome proliferator activated receptor alpha
- Rat(25747) peroxisome proliferator activated receptor alpha
- domestic guinea pig(100135604) peroxisome proliferator activated receptor alpha
- chicken(374120) peroxisome proliferator-activated receptor alpha
- naked mole-rat(101725514) peroxisome proliferator-activated receptor alpha
- Domestic Rabbit(100009308) peroxisome proliferator-activated receptor alpha
- Goat(100861393) peroxisome proliferator-activated receptor alpha
- sheep(100190976) peroxisome proliferator-activated receptor alpha
- dog(403654) peroxisome proliferator-activated receptor alpha
- Horse(100049840) peroxisome proliferator-activated receptor alpha
- domestic cat(101095837) peroxisome proliferator-activated receptor alpha
- domestic cat(100049013) peroxisome proliferator-activated receptor alpha
- cow(281992) peroxisome proliferator-activated receptor alpha
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Small Molecule - Activator
Small Molecule - Agonist
Product Number
Descripción
Especie
Fenofibrate Related Compound B, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Small Molecule - Antagonist
Antibodies
Product Number
Descripción
Reactividad de especies
Aplicación
Anti-PPAR-α antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anticuerpo anti-PPAR α, ascites fluid, Chemicon®,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-PPARα Antibody, clone 4G22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, mouse, porcine, rat
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho PPAR alpha (Ser73), from rabbit,
Reactividad de especies
bovine, human, mouse, rat
Aplicación
dot blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-PPARA antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, rat
Aplicación
western blot
Proteins
Product Number
Descripción
Especie
PPARα, ligand binding domain (170-468) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Especie
human
PPARα isotype, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Especie
human
PPARα isotype, ligand binding domain, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Especie
human
esiRNA
Product Number
Descripción
Especie