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Merck

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Sinónimos:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
Especie:
ID UniProtKB:
ID del gen:
  • Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
  • Mouse(19225) prostaglandin-endoperoxide synthase 2
  • Rat(29527) prostaglandin-endoperoxide synthase 2
  • Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2

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ELISA

Número de producto
Descripción
Especie
Human COX-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Cox2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
COX-2 (SP21) Rabbit Monoclonal Antibody, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-COX-2 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM348, purified immunoglobulin,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Cyclooxygenase-2 Antibody, Chemicon®, from rabbit,
Reactividad de especies
bovine, human, mouse, sheep
Aplicación
ELISA
western blot
Anti-COX2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Blocker

Número de producto
Descripción
Especie
N-p-Tosyl-L-phenylalanine chloromethyl ketone, ≥97% (TLC), powder,
Especie
human

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
Celecoxib, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Aceclofenac, ≥98% (HPLC),
Especie
human
Etoricoxib, VETRANAL®, analytical standard,
Especie
human
Carprofen, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Carprofen, ≥97% (HPLC),
Especie
human

Proteins

Número de producto
Descripción
Especie
Cyclooxygenase 2 human, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human PTGS2,
Especie
human
MISSION® esiRNA, targeting mouse Ptgs2,
Especie
mouse