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Merck

RP1L1

retinitis pigmentosa 1-like 1

Sinónimos:
DCDC4B
Especie:
ID UniProtKB:
ID del gen:
  • Human(94137) Summary: This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, and two C-terminal large repetitive regions, both of which contain a high percentage of glutamine and glutamic acid residues. This protein is a retinal-specific protein. Its exact length varies among individuals due to the presence of a 16aa repeat in the first C-terminal repetitive region. The 16aa repeat is encoded by the highly polymorphic 48-bp repeat, and 1-6 copies of the 16aa repeat have been identified in normal individuals. The current reference sequence shown here has a single copy of the 16aa repeat. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Mutations in this gene cause occult macular dystrophy (OMD). [provided by RefSeq, Sep 2010]
  • Mouse(271209) retinitis pigmentosa 1 homolog (human)-like 1
  • Rat(289463) retinitis pigmentosa 1-like 1
  • chicken(101667211) retinitis pigmentosa 1-like 1
  • chicken(101752129) retinitis pigmentosa 1-like 1
  • dog(486085) retinitis pigmentosa 1-like 1
  • domestic cat(101085371) retinitis pigmentosa 1-like 1
  • cow(101904170) retinitis pigmentosa 1-like 1
  • naked mole-rat(101709009) retinitis pigmentosa 1-like 1
  • Horse(100062039) retinitis pigmentosa 1-like 1
  • sheep(101110397) retinitis pigmentosa 1-like 1
  • domestic guinea pig(100718174) retinitis pigmentosa 1-like 1
  • cow(615705) retinitis pigmentosa 1-like 1

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-RP1L1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-RP1L1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Rp1l1,
Especie
mouse