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Merck

SCN1B

sodium channel, voltage-gated, type I, beta subunit

Sinónimos:
ATFB13, BRGDA5, GEFSP1
Especie:
ID UniProtKB:
ID del gen:
  • Human(6324) Summary: Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(20266) sodium channel, voltage-gated, type I, beta
  • Rat(29686) sodium channel, voltage-gated, type I, beta
  • dog(484584) sodium channel, voltage-gated, type I, beta subunit
  • domestic guinea pig(100718757) sodium channel, voltage-gated, type I, beta subunit
  • sheep(101123143) sodium channel, voltage-gated, type I, beta subunit
  • cow(618204) sodium channel, voltage-gated, type I, beta subunit
  • domestic cat(101101526) sodium channel, voltage-gated, type I, beta subunit
  • Domestic Rabbit(100009211) sodium channel, voltage-gated, type I, beta subunit
  • naked mole-rat(101709080) sodium channel, voltage-gated, type I, beta subunit

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-SCN1B, affinity isolated antibody,
Reactividad de especies
dog, guinea pig, human, rabbit, rat
Aplicación
western blot

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Scn1b,
Especie
mouse
MISSION® esiRNA, targeting human SCN1B,
Especie
human