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Merck

SF3B1

splicing factor 3b, subunit 1, 155kDa

Sinónimos:
Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155
Especie:
ID UniProtKB:
ID del gen:
  • Human(23451) Summary: This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(81898) splicing factor 3b, subunit 1
  • Rat(84486) splicing factor 3b, subunit 1
  • domestic guinea pig(100723509) splicing factor 3b, subunit 1, 155kDa
  • cow(510177) splicing factor 3b, subunit 1, 155kDa
  • Zebrafish(446117) splicing factor 3b, subunit 1
  • naked mole-rat(101707227) splicing factor 3b, subunit 1, 155kDa
  • dog(488456) splicing factor 3b, subunit 1, 155kDa
  • domestic cat(101088016) splicing factor 3b, subunit 1, 155kDa
  • Horse(100070506) splicing factor 3b, subunit 1, 155kDa
  • Goat(100861148) splicing factor 3b, subunit 1, 155kDa
  • sheep(101121573) splicing factor 3b, subunit 1, 155kDa
  • chicken(424056) splicing factor 3b, subunit 1, 155kDa

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-SF3B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-SAP155/SF3b155 Antibody, serum, from rabbit,
Reactividad de especies
bovine, human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot
Anti-SF3b155 (SAP 155) Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
western blot
Anti-SF3B1, affinity isolated antibody,
Reactividad de especies
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Anti-SF3B1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting human SF3B1,
Especie
human
MISSION® esiRNA, targeting mouse Sf3b1,
Especie
mouse