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Merck

SIAH1

siah E3 ubiquitin protein ligase 1

Sinónimos:
SIAH1A
Especie:
ID UniProtKB:
ID del gen:
  • Human(6477) Summary: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]
  • dog(487293) siah E3 ubiquitin protein ligase 1
  • Zebrafish(80955) seven in absentia homolog 1 (Drosophila)
  • sheep(101111116) siah E3 ubiquitin protein ligase 1
  • domestic cat(101090311) siah E3 ubiquitin protein ligase 1
  • domestic guinea pig(100722988) siah E3 ubiquitin protein ligase 1
  • chicken(374076) seven in absentia homolog 1 (Drosophila)
  • naked mole-rat(101702094) siah E3 ubiquitin protein ligase 1
  • cow(534655) seven in absentia homolog 1 (Drosophila)

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-SIAH1, (N-terminal) antibody produced in mouse, clone 2C5, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
Anti-SIAH1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
Anti-SIAH1, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-SIAH1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
Anti-SIAH1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
canine, human, mouse, rat
Aplicación
ELISA
immunofluorescence

western blot

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting human SIAH1, LONP2,
Especie
human