UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
Sinónimos:
GNT1, HLUGP, HLUGP1, UDPGT, UDPGT 1-6, UGT1, UGT1A6S, UGT1F
Especie:
Human UGT1A6 (54578), Rat Ugt1a6 (113992), cow UGT1A6 (286792), sheep UGT1A6 (100534643), dog UGT1A6 (403629), domestic cat UGT1A6 (100750222), domestic guinea pig Ugt1a6 (100731122), Zebrafish ugt1a6 (100384896), naked mole-rat Ugt1a6 (101707823)
ID UniProtKB:
ID del gen:
- Human(54578) Summary: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. [provided by RefSeq, Jul 2008]
- Rat(113992) UDP glucuronosyltransferase 1 family, polypeptide A6
- cow(286792) UDP glucuronosyltransferase 1 family, polypeptide A6
- sheep(100534643) UDP glucuronosyltransferase 1 family, polypeptide A6
- dog(403629) UDP glucuronosyltransferase 1 family, polypeptide A6
- domestic cat(100750222) UDP-glucuronosyltransferase 1A6
- domestic guinea pig(100731122) UDP glucuronosyltransferase 1 family, polypeptide A6
- Zebrafish(100384896) UDP glucuronosyltransferase 1 family, polypeptide A6
- naked mole-rat(101707823) UDP glucuronosyltransferase 1 family, polypeptide A6
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Antibodies
Product Number
Descripción
Reactividad de especies
Aplicación
Anti-UGT1A6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-UGT1A6 antibody produced in mouse, clone 4A10, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
Anti-UGT1A6 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Ugt1A6 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence