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ABE1000 Anti-FOXM1 Antibody

Anti-FOXM1 Antibody is an antibody against FOXM1 for use in western blotting, IHC & IP.

Anti-FOXM1 Antibody: Ficha de dados de segurança do material (FDSM) ou ficha de segurança do material (FSM), certificado de análise (CA) e certificado de qualidade (CQ), dossiês e outros documentos disponíveis.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Transcription Factors Gene Symbol: FOXM1, FKHL16, HFH11, MPP2, WIN UniProt Number: Q08050
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ABE1000
100 µg  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, IHC, IPRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE1000
      DescriptionAnti-FOXM1 Antibody
      Alternate Names
      • Forkhead box protein M1
      • Forkhead-related protein FKHL16
      • Hepatocyte nuclear factor 3 forkhead homolog 11
      • HFH-11
      • HNF-3/fork-head homolog 11
      • M-phase phosphoprotein 2
      • MPM-2 reactive phosphoprotein 2
      • Transcription factor Trident
      • Winged-helix factor from INS-1 cells
      Background InformationForkhead box M1 (FOXM1), also named HNF-3, HFH-11 or Trident, belongs to a superfamily of Fox transcription factors. FOXM1 is strongly associated with cell proliferation and plays an important role in cell cycle progression by regulating both G1/S and G2/M phases. FOXM1 is also involved in DNA damage repair, angiogenesis, apoptosis, and tissue regeneration. Recently, crucial roles of this transcription factor were found in the development and progression of many cancers including colorectal, lung, prostate, liver and breast cancer. FOXM1 levels are significantly higher and associated with tumor grade in most human tumors, rendering it a potential target of cancer diagnosis and therapies.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-FOXM1 Antibody is an antibody against FOXM1 for use in western blotting, IHC & IP.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunoprecipitation
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected FOXM1 in human testis tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to a region near the C-terminus of human FOXM1.
      EpitopeNear C-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody is expected to detect three known isoforms of FOXM1 based upon immunogen design.
      Species Reactivity
      • Human
      • Mouse
      Species Reactivity NoteHuman and Mouse. Predicted to react with Primate, Monkey, Chimpanzee and Canine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • FOXM1
      • FKHL16
      • HFH11
      • MPP2
      • WIN
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~88 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human thymus tissue lysate.

      Western Blotting Analysis: 0.25 µg/mL of this antibody detected FOXM1 in 10 µg of human thymus tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de catálogo GTIN
      ABE1000 04053252961083