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FCMAB188F Milli-Mark™ Anti-CD24-FITC Antibody, clone SN3

Detect CD24 using this Milli-Mark Anti-CD24-FITC Antibody, clone SN3 validated for use in FC.

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Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P25063
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FCMAB188F
100 tests  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMFITCMonoclonal Antibody
      Description
      Catalogue NumberFCMAB188F
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-CD24-FITC Antibody, clone SN3
      Alternate Names
      • Signal transducer CD24
      • Small cell lung carcinoma cluster 4 antigen
      Background InformationThe CD24 antigen, which has a molecular weight of 35-45 kDa, is a glycosyl phosphatidylinositol (GPI)-anchored surface molecule. It is a member of a family that also includes HSA and CD52. Cross-linking of CD24 can induce increased intracellular Ca++ in mature B lymphocytes (Turni, 2002).
      CD24 is expressed at multiple stages of B cell development, beginning with the bone marrow CD34+ pro-B-cell compartment and continuing through mature surface IgM+/IgD+ B cells. Plasma cells express very low to negligible levels of CD24 (Le Bien, 1995). CD24 is not expressed on the cell surface of normal T cells or monocytes, but is expressed on mature granulocytes (Le Bien, 1995; Fukukawa, 1986). The antigen is also present on a variety of epithelial types (Turni, 2002).
      References
      Product Information
      FormatFITC
      HS Code3002 15 90
      Control
      • PBMCs
      PresentationPurified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
      Quality LevelMQ100
      Applications
      ApplicationDetect CD24 using this Milli-Mark Anti-CD24-FITC Antibody, clone SN3 validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenIsolated membrane fraction of the pre-B leukemic cell line NALM-1.
      CloneSN3
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityAntibody recognizes Human CD24 antigen.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight35-45 kDa (Turni, 2002)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using human PBMCs
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de catálogo GTIN
      FCMAB188F 04053252289156

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      Categorias

      Life Science Research > Antibodies and Assays > Primary Antibodies