DNA
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Histones and Histone Modifications | Life Science Research | Merck
Histone modifications regulate DNA transcription, repair, recombination, and replication, and can alter local chromatin architecture. Understanding histone modifications is key to uncovering epigenetic mechanisms of gene regulation. Merck grasps the complexity of this research and provides a growing line of kits, antibodies, and assays for studying histones and their modifications. Merck offers over 600 validated antibodies, recombinant proteins, and kits to analyze histone and histone-variant phosphorylation, methylation, acetylation, ubiquitination, and citrullination-the most widely studied histone modifications in epigenetics today. -
DNA Markers | Life Science Research | Merck
Our DNA markers contain sets of DNA species in convenient, easy-to-remember sizes for routine use in plasmid cloning. They also include an extra vial of 6X DNA gel loading buffer. -
DNA Purification | Genomic Analysis - Life Science Research | Merck
DNA purification of DNA fragments and subcloning is required in downstream manipulations of PCR products, such as restriction digests, ligation or hybridization. -
DNA Methylation | Life Science Research | Merck
DNA methylation is involved in the regulation of many cellular processes, including chromosome stability, chromatin structure, X chromosome inactivation, embryonic development, and transcription. -
Water for DNA Sequencing - Lab Water Solutions | Application | Water Purification | Merck
Merck has developed a range of solutions adapted to the needs of scientists performing DNA sequencing. -
DNA Methylation | Life Science Research | Merck
DNA methylation is involved in the regulation of many cellular processes, including chromosome stability, chromatin structure, X chromosome inactivation, embryonic development, and transcription. DNA methylation occurs mainly at the 5' position of cytosine bases and is mediated by enzymes called DNA methyltransferases (DNMT). Regions of methylated DNA can be bound by a variety of methylated DNA binding proteins (MBD). -
DNA Structure, Damage and Repair | Life Science Research | Merck
Studying the mechanisms by which cells control changes in DNA structure and respond to DNA damage will help to elucidate the factors that cause aging, cellular degeneration, cancer, and death. Merck has the antibody solutions you need for your research. -
Plasmid DNA Recommended Devices and Filters | Vaccines Learning Center | Biopharmaceutical Manufacturing | Merck
We provide details on process development devices for recommended filters and alternatives since the ideal solution will vary based on each fluid stream. -
Cleavage Enzymes | Life Science Research | Merck
Cleavage enzymes were found to cut DNA at specific sites, creating unique, gene-size fragments that could be fused together in the laboratory. Learn more about our best selling products designed for highly specific cleavage of fusion proteins followed by removal of enterokinase, factor Xa, HRV 3C protease and thrombin.