GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
Synonymes:
ECA4, EJM, EJM5
Espèce(s):
Human GABRA1 (2554), Mouse Gabra1 (14394), Rat Gabra1 (29705), domestic guinea pig Gabra1 (100721626), cow GABRA1 (780973), dog GABRA1 (489143), naked mole-rat Gabra1 (101719179), Zebrafish gabra1 (768183), sheep GABRA1 (101117759), chicken GABRA1 (374214)
ID UniProtKB:
ID du gène:
- Human(2554) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14394) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
- Rat(29705) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic guinea pig(100721626) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- cow(780973) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- dog(489143) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- naked mole-rat(101719179) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- Zebrafish(768183) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- sheep(101117759) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- chicken(374214) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic cat(100286792) gamma-aminobutyric acid (GABA) A receptor, alpha 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Agonist
Numéro du produit
Description
Espèce(s)
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Small Molecule - Allosteric Modulator
Numéro du produit
Description
Espèce(s)
Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Small Molecule - Antagonist
Numéro du produit
Description
Espèce(s)
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-GABA antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
drosophila, rat, wide range
Application
dot blot
immunohistochemistry
immunohistochemistry
Monoclonal Anti-GABA antibody produced in mouse, clone GB-69, ascites fluid,
Espèces réactives
wide range
Application
ELISA
dot blot
immunofluorescence
immunohistochemistry
dot blot
immunofluorescence
immunohistochemistry
Anti-GABA Antibody, serum, Chemicon®,
Espèces réactives
all, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-GABA A Receptor β2/3 Antibody, clone 62-3G1, Upstate®, from mouse,
Espèces réactives
bovine, human, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-GABA Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
all, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Small Molecule - Inhibitor
Small Molecule - Ligand
Numéro du produit
Description
Espèce(s)
Small Molecule - Mixed Agonist/Antagonist
Numéro du produit
Description
Espèce(s)
Phénol solution, BioReagent, Equilibrated with 10 mM Tris HCl, pH 8.0, 1 mM EDTA, Molecular Biology,
Espèce(s)
human
Phénol solution, Saturated with 0.01 M citrate buffer, pH 4.3 ± 0.2, BioReagent, Molecular Biology,
Espèce(s)
human