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Merck

Y0000619

Gaïacol

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2-Méthoxyphénol, Éther monométhylique de catéchol, Éther monométhylique de pyrocatéchol

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A propos de cet article

Formule linéaire :
(CH3O)C6H4OH
Numéro CAS:
Poids moléculaire :
124.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
508112
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grade

pharmaceutical primary standard

vapor density

4.27 (vs air)

vapor pressure

0.11 mmHg ( 25 °C)

API family

guaiacol

manufacturer/tradename

EDQM

refractive index

n20/D 1.543 (lit.)

bp

205 °C (lit.)

mp

26-29 °C (lit.)

density

1.129 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccccc1O

InChI

1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3

InChI key

LHGVFZTZFXWLCP-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Guaiacol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Le gaïacol, en association avec le 2,4,6-trichloroanisole, est responsable du goût de bouchon dans le vin. Une méthode a été développée pour l′extraction et la quantification de ces deux composés.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

179.6 °F - closed cup

flash_point_c

82 °C - closed cup



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Woo-Cheol Sim et al.
Biochemical pharmacology, 90(4), 414-424 (2014-06-24)
Collaborative regulation of liver X receptor (LXR) and sterol regulatory element binding protein (SREBP)-1 are main determinants in hepatic steatosis, as shown in both animal models and human patients. Recent studies indicate that selective intervention of overly functional LXRα in
Tao Liu et al.
The Analyst, 139(17), 4315-4321 (2014-07-06)
The rapid and sensitive detection of Alicyclobacillus acidoterrestris (AA) has become very important due to the frequent occurrence of fruit juice spoilage by AA. In the present study, using guaiacol, both as the metabolic product of AA related to its
Hye Jin Jung et al.
PloS one, 9(11), e112256-e112256 (2014-11-15)
Silver materials have been widely used in diverse fields. However, their toxicity and their mechanism, especially in different forms, have not been studied sufficiently. Thus, cytotoxicity, apoptosis, and interleukin-1beta (IL-1β) production were investigated using macrophage-like THP-1 cells in the presence