D9190
DCEBIO
≥98% (HPLC), solid
Synonyme(s) :
5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazole-2-one
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A propos de cet article
Formule empirique (notation de Hill) :
C9H8N2OCl2
Numéro CAS:
Poids moléculaire :
231.08
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Service technique
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Laissez-nous vous aiderQuality Level
assay
≥98% (HPLC)
form
solid
color
white to off-white
solubility
DMSO: >10 mg/mL
SMILES string
CCN1C(=O)Nc2cc(Cl)c(Cl)cc12
InChI
1S/C9H8Cl2N2O/c1-2-13-8-4-6(11)5(10)3-7(8)12-9(13)14/h3-4H,2H2,1H3,(H,12,14)
InChI key
LKHRMULASXZCLG-UHFFFAOYSA-N
Gene Information
Biochem/physiol Actions
DCEBIO facilitates Cl− secretion in the epithelia by activating K+ and Cl− currents.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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David F Stowe et al.
Journal of cardiovascular pharmacology, 70(5), 314-328 (2017-08-05)
Both big (BKCa) and small (SKCa) conductance Ca-sensitive K channels are present in mammalian cardiac cell mitochondria (m). We used pharmacological agonists and antagonists of BKCa and SKCa channels to examine the importance of endogenous opening of these channels and
Amy N Savitski et al.
Respiratory research, 10, 120-120 (2009-12-01)
Secondhand smoke (SHS) exposure is an independent risk factor for asthma, rhinosinusitis, and more severe respiratory tract infections in children and adults. Impaired mucociliary clearance with subsequent mucus retention contributes to the pathophysiology of each of these diseases, suggesting that
Naoto Fujii et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 318(2), R390-R398 (2020-01-09)
Local skin heating to 42°C causes cutaneous thermal hyperemia largely via nitric oxide (NO) synthase (NOS)-related mechanisms. We assessed the hypothesis that ATP-sensitive K+ (KATP) channels interact with NOS to mediate cutaneous thermal hyperemia. In 13 young adults (6 women