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Merck

D2954000

Dobutamine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

(±)-3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-β-phenethylamine hydrochloride

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A propos de cet article

Formule empirique (notation de Hill) :
C18H23NO3 · HCl
Numéro CAS:
49745-95-1
Poids moléculaire :
337.84
NACRES:
NA.24
PubChem Substance ID:
329798764
UNSPSC Code:
41116107
MDL number:
MFCD00153795

Principaux documents

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Nom du produit

Dobutamine hydrochloride, European Pharmacopoeia (EP) Reference Standard

InChI key

BQKADKWNRWCIJL-UHFFFAOYSA-N

SMILES string

Cl[H].CC(CCc1ccc(O)cc1)NCCc2ccc(O)c(O)c2

InChI

1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H

grade

pharmaceutical primary standard

API family

dobutamine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... ADRB1(153), ADRB2(154)

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Catégories apparentées

Application

Dobutamine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 2

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number

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X Monnet et al.
British journal of anaesthesia, 111(5), 743-749 (2013-06-27)
We tested the ability of mean acceleration (Acc) and peak velocity (V peak) of the aortic velocity signal measured by oesophageal Doppler to reflect left ventricular (LV) systolic performance. We included critically ill patients in whom a fluid challenge (n=25)
Martin G Schultz et al.
American journal of hypertension, 26(4), 557-566 (2013-03-08)
The J-curve relationship between brachial diastolic blood pressure (DBP) and mortality is believed to be mediated through reduced myocardial perfusion. This study aimed to determine the relationship between DBP and subendocardial perfusion in patients with and without coronary artery disease
Neeraj Singh et al.
Transplantation, 94(12), 1224-1229 (2012-12-25)
The utility of cardiac stress testing as a risk-stratification tool before kidney transplantation remains debatable owing to discordance with coronary angiography and outcome yields at different centers. We conducted a retrospective study of 273 diabetic kidney transplant recipients from 2006
Marie-Annick Clavel et al.
JACC. Cardiovascular imaging, 6(2), 175-183 (2013-03-16)
The objective of this study was to examine the value of stress-echocardiography in patients with paradoxical low-flow, low-gradient (PLFLG) aortic stenosis (AS). The projected aortic valve area (AVAProj) at a normal flow rate was calculated in 55 patients with PLFLG
Edmund M T Lau et al.
Chest, 146(4), 959-966 (2014-03-15)
Stress testing of the pulmonary circulation (via increasing pulmonary blood flow) can reveal abnormal mean pulmonary artery pressure-cardiac output (mPpa-Q) responses, which may facilitate early diagnosis of pulmonary vascular disease. We investigated the application of dobutamine stress echocardiography (DSE) for
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