Accéder au contenu
Merck

PHR1280

Xylitol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Xylite

Se connecter pour consulter les tarifs organisationnels et contractuels.

Sélectionner une taille de conditionnement

A propos de cet article

Formule linéaire :
HOCH2[CH(OH)]3CH2OH
Numéro CAS:
87-99-0
Poids moléculaire :
152.15
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823276
EC Number:
201-788-0
Beilstein/REAXYS Number:
1720523
MDL number:
MFCD00064292

Principaux documents

Voir toute la documentation
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aider
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aider

SMILES string

OC[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5+

InChI key

HEBKCHPVOIAQTA-SCDXWVJYSA-N

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. X0080000, traceable to USP 1720600

API family

xylitol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

94-97 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Catégories apparentées

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Xylitol is a naturally occurring polyhydric sugar alcohol with high sweetening power and anticariogenic properties.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Xylitol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by capillary isotachophoresis.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC4431 in the slot below. This is an example certificate only and may not be the lot that you receive.

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Separation and determination of sorbitol and xylitol in multi-component pharmaceutical formulations by capillary isotachophoresis
Pospisilova M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 17(3), 387-392 (1998)
The effect of xylitol on dental caries and oral flora
Nayak PA, et al.
Clinical, cosmetic and investigational dentistry, 6, 89-89 (2014)
Eun Joong Oh et al.
Metabolic engineering, 15, 226-234 (2012-10-30)
As Saccharomyces cerevisiae cannot utilize xylose as a carbon source, expression of XYL1 coding for xylose reductase (XR) from Scheffersomyces (Pichia) stipitis enabled production of xylitol from xylose with a high yield. However, insufficient supply of NAD(P)H for XR and
Xiaoxiao Guo et al.
Bioresource technology, 128, 547-552 (2012-12-06)
In this study, an integrated xylitol production pathway, directly using xylan as the substrate, was constructed in Candida tropicalis BIT-Xol-1 which could efficiently convert xylose into xylitol. In order to consolidate this bioprocessing, a β-1,4-xylanase gene (atn) and a β-xylosidase
L Zhan et al.
Journal of dental research, 91(7 Suppl), 85S-90S (2012-09-21)
The aim of the study was to investigate the efficacy of the use of xylitol-containing tooth-wipes in preventing dental caries in young children. In a double-blinded randomized controlled clinical trial, 44 mothers with active caries and their 6- to 35-month-old
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique