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PHR1452

Carprofen

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Carprofen, CAR, 6-Chloro-α-methyl-9H-carbazole-2-acetic acid

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A propos de cet article

Formule empirique (notation de Hill) :
C15H12ClNO2
Numéro CAS:
53716-49-7
Poids moléculaire :
273.71
NACRES:
NA.24
PubChem Substance ID:
329822612
UNSPSC Code:
41116107
EC Number:
258-712-4
MDL number:
MFCD00079028
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Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0000846, traceable to USP 1096699

API family

carprofen

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C(O)=O)c1ccc2c(c1)[nH]c3ccc(Cl)cc23

InChI

1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)

InChI key

PUXBGTOOZJQSKH-UHFFFAOYSA-N

Gene Information

human ... PTGS2(5743)

General description

Carprofen is a nonsteroidal anti-inflammatory drug (NSAID), majorly used as equine medicine. It is known to be commonly present in the environment as a contaminant.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Carprofen has been used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA3000 in the slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

A novel two-dimensional liquid chromatographic system for the online toxicity prediction of pharmaceuticals and related substances
Li L, et al.
Journal of Hazardous Materials, 293, 15-20 (2015)
Capillary electrophoresis for the analysis of non-steroidal anti-inflammatory drugs
Macia A, et al.
TrAC, Trends in Analytical Chemistry, 26(2), 133-153 (2007)
Nonsteroidal anti-inflammatory drug metabolism studies in horses in view of doping control: analytical strategies and challenges
Waraksa E, et al.
TrAC, Trends in Analytical Chemistry, 11(30), 3767-3792 (2019)
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