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Merck

PHR1552

Chloroforme

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Chloroforme, Trichlorométhane, Trichlorure de méthylidyne

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A propos de cet article

Formule empirique (notation de Hill) :
CHCl3
Numéro CAS:
Poids moléculaire :
119.38
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-663-8
Beilstein/REAXYS Number:
1731042
MDL number:
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InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

InChI

1S/CHCl3/c2-1(3)4/h1H

SMILES string

ClC(Cl)Cl

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1601383

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

CofA

current certificate can be downloaded

packaging

ampule of 3x1.2 mL each

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

mp

−63 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

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General description

Chloroform is a volatile chlorinated organic solvent whose vapors have a narcotic effect. It is a widely used industrial and laboratory solvent. It is also used in the manufacture of many pesticides, rubber, resin, and wax.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Chloroform may be used as a solvent reference standard for the determination of the analyte in bulk drug and dosage forms by spectrophotometry and spectrofluorimetry techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA8822 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash


Certificats d'analyse (COA)

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