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Merck

PHR1561

Tétrahydrofurane

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Tétrahydrofurane, Oxolane, Oxyde de butylène, Oxyde de tétraméthylène

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A propos de cet article

Formule empirique (notation de Hill) :
C4H8O
Numéro CAS:
109-99-9
Poids moléculaire :
72.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823470
EC Number:
203-726-8
Beilstein/REAXYS Number:
102391
MDL number:
MFCD00005356

Principaux documents

Voir toute la documentation
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Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1601770

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C), 143 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

610 °F

expl. lim.

1.8-11.8 %

packaging

ampule of 3x1.2 mL each

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.407 (lit.)

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

density

0.889 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Catégories apparentées

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Tetrahydrofuran is a saturated cyclic ether with a potential use as a biofuel. It is used for the manufacture of polyurethanes.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC0275 in the slot below. This is an example certificate only and may not be the lot that you receive.

signalword

Danger

target_organs

Central nervous system, Respiratory system

supp_hazards

EUH019

Classe de stockage

3 - Flammable liquids

flash_point_f

-6.2 °F - closed cup

flash_point_c

-21.2 °C - closed cup

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Szycher's Handbook of Polyurethanes (1999)
Fabrice Giusti et al.
The Journal of membrane biology, 247(9-10), 909-924 (2014-03-22)
Amphipols are short amphipathic polymers that can substitute for detergents at the hydrophobic surface of membrane proteins (MPs), keeping them soluble in the absence of detergents while stabilizing them. The most widely used amphipol, known as A8-35, is comprised of
Gyan P Mishra et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(2), 397-405 (2014-06-17)
Biodegradable poly(ethyleneglycol)-poly(valerolactone)-poly(ethyleneglycol) [PEG-PVL-PEG] copolymers were synthesized through ring opening polymerization of δ-valerolactone (VL) followed by the coupling of monomethoxy poly(ethyleneglycol-poly(valerolactone) (mPEG-PVL) with hexamethylene diisocyanate (HDI). The copolymers were characterized by (1)H NMR, FT-IR, and GPC. Block copolymers of PEG and
Konstantinos E Farsalinos et al.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 17(2), 168-174 (2014-09-03)
The purpose of this study was to evaluate sweet-flavored electronic cigarette (EC) liquids for the presence of diacetyl (DA) and acetyl propionyl (AP), which are chemicals approved for food use but are associated with respiratory disease when inhaled. In total
Lucie Nováková et al.
Analytica chimica acta, 853, 647-659 (2014-12-04)
The potential and applicability of UHPSFC-MS/MS for anti-doping screening in urine samples were tested for the first time. For this purpose, a group of 110 doping agents with diverse physicochemical properties was analyzed using two separation techniques, namely UHPLC-MS/MS and
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