X114

Triton^™ X-114

Name: Triton<SUP>™</SUP> X-114
Brand: SIAL

laboratory grade

Synonyme(s) :

(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol, Polyethylene glycol tert-octylphenyl ether

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A propos de cet article

Formule linéaire :

(C₂H₄O)n C₁₄H₂₂O, n = 7 or 8

Numéro CAS:

9036-19-5

UNSPSC Code:

12161900

NACRES:

NA.21

PubChem Substance ID:

24902129

MDL number:

MFCD00128254

Beilstein/REAXYS Number:

2315025

Principaux documents

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Nom du produit

Triton^™ X-114, laboratory grade

InChI

1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3

SMILES string

CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1

InChI key

HNLXNOZHXNSSPN-UHFFFAOYSA-N

grade

laboratory grade

description

non-ionic

mol wt

average mol wt 537

composition

t-Oct-C₆H₄-(OCH₂CH₂)_xOH, x = 7-8

refractive index

n20/D 1.488 (lit.)

CMC

0.2 mM (20-25°C)

transition temp

pour point ~−9 °C
cloud point 23 °C

HLB

12.4

Quality Level

200

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Catégories apparentées

Chemistry & Biochemicals

Biochemicals

Detergents - Anionic, Cationic, Zwitterionic, Anti-foaming

Application

Triton^™ X-114 has been used:

To remove endotoxin from solutions of protein using phase separation technique
In the extraction and purification of DNA from endotoxin
In the biphasic extraction of lipoproteins from bacterial cell wall
As a non-ionic detergent with a low cloud point (23 °C) enabling protein solubilization with phase-partitioning of hydrophilic from amphiphilic proteins

General description

Triton^™ X-114 is a nonionic detergent. It is a good detergent for solubilizing membranes having reversible phase-separation property useful for the separation of intrinsic membrane proteins. Solution of Triton^™ X-114 is homogeneous at 0°C but phase separation into aqueous phase and a detergent phase occurs above 20°C. Phase separation of proteins in solutions of Triton^™ X-114 has been investigated. This octylphenol ethoxylate is compatible with anionic, cationic, and other nonionic surfactants and chemically stable in most acidic & alkaline solutions.

Legal Information

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

pictograms

GHS05,GHS07,GHS09

signalword

Danger

hcodes

H302,H315,H318,H410

pcodes

P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2

Classe de stockage

10 - Combustible liquids

wgk

WGK 3

flash_point_f

483.8 °F - closed cup

flash_point_c

251 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificats d'analyse (COA)

Lot/Batch Number

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Conserved Citrullinating Exoenzymes in Porphyromonas Species.

G Gabarrini et al.

Journal of dental research, 97(5), 556-562 (2018-01-05)

Porphyromonas gingivalis is one of the major oral pathogens implicated in the widespread inflammatory disorder periodontitis. Moreover, in recent years, P. gingivalis has been associated with the autoimmune disease rheumatoid arthritis. The peptidylarginine deiminase enzyme of P. gingivalis (PPAD) is

Comparison of LC-MS/MS-based targeted proteomics and conventional analytical methods for monitoring breast cancer resistance protein expression.

Huanhuan Li et al.

Life sciences, 231, 116548-116548 (2019-06-11)

Multidrug resistance is a major obstacle in chemotherapy, which is mainly caused by the overexpression of ATP-binding cassette (ABC) transporters. Breast cancer resistance protein (BCRP) is one of the ABC transporters and is strongly associated with multidrug resistance. Results of

Mechanism and function of a newly identified CpG DNA motif in human primary B cells.

Hartmann G and Krieg A M

Journal of Immunology, 164(2), 944-953 (2000)

Chimeric ZHHH neuroglobin acts as a cell membrane-penetrating inducer of neurite outgrowth.

Nozomu Takahashi et al.

FEBS open bio, 7(9), 1338-1349 (2017-09-15)

Neuroglobin (Ngb) is a heme protein expressed in the vertebrate brain. We previously engineered a chimeric Ngb protein, in which module M1 of human Ngb is replaced by that of zebrafish Ngb, and showed that the chimeric ZHHH Ngb has

Mycobacterium tuberculosis LprG (Rv1411c): a novel TLR-2 ligand that inhibits human macrophage class II MHC antigen processing.

Gehring A J, et al.

Journal of Immunology, 173(4), 2660-2668 (2004)

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Triton^™ X-114

laboratory grade