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Merck

Y0000754

Methenamine

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Hexamethylenetetramine, 1,3,5,7-Tetraazatricyclo[3.3.1.13,7]decane, Hexamine, Methenamine, Urotropine

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A propos de cet article

Formule empirique (notation de Hill) :
C6H12N4
Numéro CAS:
Poids moléculaire :
140.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2018
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InChI

1S/C6H12N4/c1-7-2-9-4-8(1)5-10(3-7)6-9/h1-6H2

SMILES string

C1N2CN3CN1CN(C2)C3

InChI key

VKYKSIONXSXAKP-UHFFFAOYSA-N

grade

pharmaceutical primary standard

vapor pressure

<0.01 mmHg ( 20 °C)

API family

methenamine

autoignition temp.

770 °F

manufacturer/tradename

EDQM

mp

280 °C (subl.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Methenamine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

FlameExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Flam. Sol. 2 - Skin Sens. 1B

Classe de stockage

4.1B - Flammable solid hazardous materials

wgk

WGK 1

flash_point_f

482.0 °F - closed cup

flash_point_c

250 °C - closed cup


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Lot/Batch Number

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Consulter la Bibliothèque de documents

Adriana Luk et al.
The Malaysian journal of pathology, 36(2), 71-81 (2014-09-10)
The incidence of infective endocarditis is 1.5-4.95 cases per 100,000 individuals per year, with a mortality of 14-46% 1-year post infection. The management and decision to operate on selected patients remains controversial. Our study reviews cases of native and prosthetic
Andreas Lemmerer et al.
Chemical communications (Cambridge, England), 48(13), 1883-1885 (2011-12-03)
The tetrahedral arrangement of hydrogen bonding donor and acceptor groups is used to rationalise the design of a diamondoid network; however, a single proton transfer renders the four sites inequivalent, and results in two polymorphs of the title molecular salt
Lorena Vidal et al.
Journal of chromatography. A, 1285, 7-14 (2013-03-12)
Quaternary ammonium-functionalized silica materials were synthesized and applied for solid-phase extraction (SPE) of aromatic amines, which are classified as priority pollutants by US Environmental Protection Agency. Hexamethylenetetramine used for silica surface modification for the first time was employed as SPE
R Gleckman et al.
American journal of hospital pharmacy, 36(11), 1509-1512 (1979-11-01)
The mechanism of action, spectrum of antimicrobial activity, pharmacokinetics, adverse effects, therapeutic use, and dosage of methenamine hippurate and methenamine mandelate are reviewed. The antimicrobial activity of methenamine depends on its conversion in the urine to formaldehyde. Formaldehyde's spectrum of
P Restani et al.
Food additives and contaminants, 9(5), 597-605 (1992-09-01)
Formaldehyde (FA) and hexamethylenetetramine (HMT) are used in cheese production to control gas-forming clostridia; FA also occurs naturally in some foods at levels of 1-20 mg/kg. The toxicology of FA and HMT are briefly discussed together with their reaction in

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