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Merck

Y0001099

Valaciclovir impurity G

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

4-(Dimethylamino)pyridine, N,N-Dimethylpyridin-4-amine, DMAP

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A propos de cet article

Formule empirique (notation de Hill) :
C7H10N2
Numéro CAS:
1122-58-3
Poids moléculaire :
122.17
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329831263
MDL number:
MFCD00006418
Beilstein/REAXYS Number:
110354

Principaux documents

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InChI

1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

SMILES string

CN(C)c1ccncc1

InChI key

VHYFNPMBLIVWCW-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

valacyclovir

manufacturer/tradename

EDQM

mp

108-110 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Catégories apparentées

General description

4-(Dimethylamino)pyridine (DMAP) is an excellent catalyst for acylation of hindered alcohols and in chemical transformations. It is highly nucleophilic in nature.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

A highly efficient catalyst for acylation reactions

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1

target_organs

Nervous system

Classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

255.2 °F

flash_point_c

124 °C

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Certificats d'analyse (COA)

Lot/Batch Number

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Configurationally Stable Biaryl Analogues of 4-(Dimethylamino) pyridine: A Novel Class of Chiral Nucleophilic Catalysts.
Spivey, Alan C., et al.
The Journal of Organic Chemistry, 64.26, 9430-9443 (1999)
Masahiro Murakami et al.
Acta biomaterialia, 10(11), 4723-4729 (2014-07-20)
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Bryan Hoang et al.
International journal of pharmaceutics, 471(1-2), 224-233 (2014-05-24)
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Taxanes are a class of anticancer agents with a broad spectrum and have been widely used to treat a variety of cancer. However, its long-term use has been hampered by accumulating toxicity and development of drug resistance. The most extensively
Junya Ito et al.
Journal of chromatography. A, 1386, 53-61 (2015-02-18)
Increasing evidence suggests that phospholipid peroxidation plays important roles in the pathogenesis of various diseases, such as atherosclerosis. With regard to the biochemical processes that initiate phospholipid peroxidation in vivo, enzymatic conversion of phosphatidylcholine to phosphatidylcholine hydroperoxide (PCOOH) by lipoxygenase
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