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Merck

02286

Polyvinylpyrrolidone

Synonyme(s) :

PVP, Polyvidone, Povidone

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A propos de cet article

Formule linéaire :
(C6H9NO)n
Numéro CAS:
NACRES:
NA.25
UNSPSC Code:
12162002
MDL number:
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InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

impurities

≤1 ppm hydrazine, ≤10 ppm heavy metals (verified on random samples only), ≤10 ppm lead (verified on random samples only), ≤10 ppm vinylpyrrolidinone, ≤3.0% 2-pyrrolidone, ≤400 ppm peroxides (as H2O2), ≤5.0% water, ≤500 ppm aldehydes (as acetaldehyde), ≤5000 ppm formic acid, 12.0-12.8% nitrogen (anhydrous basis)

ign. residue

≤0.1% (verified on random samples only)

pH

3.0-5.0

suitability

complies for Infrared spectrum

application(s)

sample preservation

Quality Level

Application

The Kollidon products consist of soluble and insoluble grades of polyvinylpyrrolidone (PVP) of various molecular weights and particle sizes. It is used as dry binders, film-formers, stabilizers in suspensions, dispersants for pigments, enzyme stabilisiers and bioavailablility improvers.
Kollidon SR is a blend of polyvinyl acetate and povidone (K 30) in the ratio 8:2 for use as matrix-forming agent. This research grade product is intended for use in R&D and development only.

Other Notes

Le polyvinylpyrrolidone est un constituant de la solution de Denhardt et est inclus à une concentration de 1 % (p/v) dans la solution-mère standard 50X.

Legal Information

Kollidon is a registered trademark of BASF SE

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Yan-Yan Yin et al.
Inorganic chemistry, 51(8), 4784-4790 (2012-03-31)
Chiral Ni(II) coordination compounds with structures of [NiL(H(2)O)(3)] (1) and {[NiL(H(2)O)]·0.5H(2)O}(n) (2) (H(2)L = thiazolidine 2,4-dicaboxlic acid) have been successfully synthesized by the reaction of Ni(CH(3)COO)(2)·4H(2)O and H(2)L in aqueous solution at 25 and 80 °C, respectively. From the same
Camila Braga Dornelas et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 14(1), 17-35 (2011-04-20)
This work describes the preparation of new nanocomposites based on lamellar silicates (AAM-alkyl ammonium montmorillonite) obtained by the intercalation of PVP K30 and glyceril monostearate. By XRD, TGA and DSC analysis the AAM was characterized and its compactation characteristics, functionality
Jianxin Zhang et al.
International journal of pharmaceutics, 414(1-2), 210-217 (2011-06-02)
Nanothermal analysis (NTA) supported by atomic force microscopy imaging has been used to study the changes that occur at the surfaces of solid dispersions of the drug felodipine and the water soluble polymer, polyvinylpyrrolidone (PVP) on exposure to standard pharmaceutical
Ajit S Narang et al.
Journal of pharmaceutical sciences, 101(1), 127-139 (2011-11-24)
Reactive peroxides in povidone often lead to degradation of oxidation-labile drugs. To reduce peroxide concentration in povidone, the roles of storage conditions, antioxidants, and silicates were investigated. Povidone alone and its physical mixtures with ascorbic acid, propyl gallate, sodium sulfite
Liyun Ren et al.
Nanoscale, 5(6), 2337-2345 (2013-02-09)
PLLA fibrous tissue scaffolds with controlled fiber nanoscale surface roughness are fabricated with a novel centrifugal jet spinning process. The centrifugal jet spinning technique is a highly efficient synthesis method for micron- to nano-sized fibers with a production rate up

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