RAB0460
Human TGF-β 1 ELISA Kit
for serum, plasma, and cell culture supernatants
Synonyme(s) :
TGF-beta-1, Transforming growth factor beta-1
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A propos de cet article
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... TGFB1(7040)
Input:
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type cell culture supernatant(s)
sample type plasma
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
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Laissez-nous vous aiderspecies reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 0.0823-60 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TGFB1(7040)
Catégories apparentées
General description
The Human TGF-β 1 ELISA (Enzyme-Linked mmunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human TGF-β 1 in serum, plasma, cell culture supernatants.
Immunogen
Recombinant Human TGF-β 1
Application
For research use only. Not for use in diagnostic procedures.
Human transforming growth factor-β1 (TGF-β1) ELISA Kit has been used to measure level of TGF-β1 released from tubular cells.
Human transforming growth factor-β1 (TGF-β1) ELISA Kit has been used to measure level of TGF-β1 released from tubular cells.
Biochem/physiol Actions
Transforming growth factor-β1 (TGF-β1) is a pluripotential cytokine that plays a vital role in the homeostasis of peripheral CD4+CD25+ regulatory T cells and regulation of FOXP3 (forkhead box P3) expression in vivo. Binding of TGF-β1 to its receptor, activates members of the SMAD protein family involved in gene regulation. Study shows that reduced expression of circulating transforming growth factor-β1 (TGF-β1) might contribute to systemic lupus erythematosus (SLE) development. Polymorphism of TGF-β1 is associated with pathogenesis of rheumatoid arthritis (RA) and pneumoconiosis. Serum TGF-β1 expression is elevated in systemic sclerosis (SSc) patients. Serum TGF-β1 functions as a potential biomarker of Guillain-Barré syndrome (GBS) and SSc.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Composants de kit également disponibles séparément
Réf. du produit
Description
FDS
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Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Classe de stockage
8A - Combustible corrosive hazardous materials
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XueXuan Zhang et al.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 59, 110-117 (2017-04-19)
To investigate PI3K-Akt-mTOR signaling pathway changes and the proliferation of FoxP3+Treg cells in patients with active tuberculosis. We isolated PBMCs and CD4+CD25+FoxP3+Treg cells from peripheral blood collected from patients with active tuberculosis and healthy controls. We compared the proportion and
Yali Zhou et al.
Experimental and therapeutic medicine, 21(6), 617-617 (2021-05-04)
The present study aimed to evaluate changes in bone mineral density, 25-hydroxyvitamin D3 [25-(OH)D3] and inflammatory factors in patients with hyperthyroidism, in order to determine the correlations with the pathogenesis of hyperthyroidism. A total of 55 patients with hyperthyroidism (observation
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells.
Marie JC
The Journal of Experimental Medicine, 201(7), 1061-1067 (2005)
Qin Zhang et al.
Experimental and therapeutic medicine, 17(3), 1717-1727 (2019-02-21)
The aim of the present study was to investigate the expression and role of transforming growth factor (TGF)-β1/phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3KC3) in the peripheral blood in patients with hypertension. A total of 28 patients with primary hypertension
Reassessing the Role of the Active TGF-?1 as a Biomarker in Systemic Sclerosis: Association of Serum Levels with Clinical Manifestations.
Dantas AT
Disease Markers (2016)
Contenu apparenté
Instructions
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