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1179333

USP

Dexmedetomidine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

(+)-Medetomidine hydrochloride, (S)-Medetomidine hydrochloride, 4-[(S)-α,2,3-Trimethylbenzyl]imidazole monohydrochloride, 5-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride

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A propos de cet article

Formule empirique (notation de Hill) :
C13H16N2 · HCl
Numéro CAS:
145108-58-3
Poids moléculaire :
236.74
MDL number:
MFCD07772269
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

API family

dexmedetomidine, medetomidine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[Cl-].[N+H2]1C=NC=C1[C@@H](C)c2c(c(ccc2)C)C

InChI

1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1

InChI key

VPNGEIHDPSLNMU-MERQFXBCSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexmedetomidine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Dexmedetomidine Injection

Biochem/physiol Actions

Dexmedetomidine hydrochloride is a highly potent and selective α2-adrenergic agonist with analgesic and sedative properties, the (+)-isomer of medetomidine. Dexmedetomidine hydrochloride is used clinically as an anesthetic agent to reduce anxiety and tension and promote relaxation and sedation without causing respiratory depression.
Dexmedetomidine hydrochloride is a highly potent and selective α2-adrenergic agonist with analgesic and sedative properties.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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pictograms

Exclamation markEnvironment
GHS07,GHS09

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT SE 3

target_organs

Central nervous system

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Consulter la Bibliothèque de documents

Dexmedetomidine Hydrochloride
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 45(2), 1302-1302 (2020)
Dexmedetomidine Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(4), 1304-1304 (2018)