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A propos de cet article
Formule empirique (notation de Hill) :
C19H21N5O4 · HCl
Numéro CAS:
Poids moléculaire :
419.86
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4303561
Service technique
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pharmaceutical primary standard
API family
prazosin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
Cl.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4
InChI
1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H
InChI key
WFXFYZULCQKPIP-UHFFFAOYSA-N
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
General description
Prazosin hydrochloride is an alpha-adrenergic blocking agent, employed as an antihypertensive drug for the treatment of high blood pressure. It lowers the blood pressure by binding to the alpha receptors thereby relaxing the blood vessels.
Application
It was used as an α1-adrenergic receptors antagonist, in a study performed to understand the influence of dopamine on uterine motility of rats in vitro.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - STOT RE 2 - STOT SE 3
Classe de stockage
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
target_organs
Central nervous system
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Influence of dopamine on rat uterine motility in vitro.
Czerski, A., et al.
Acta Veterinaria Brno, 74.1, 9-15 (2005)
Quantitative analysis of prazosin hydrochloride in pharmaceutical formulation by prazosin potentiometric sensor based on computational investigation.
Faridbod, Farnoush, et al.
International Journal of Electrochemical Science, 5, 653-667 (2010)
Physiologic evaluation of a new antihypertensive agent: prazosin HCl.
Koshy MC
Circulation, 55(3), 533-537 (1977)