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Merck

1570009

USP

Promethazine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride

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A propos de cet article

Formule empirique (notation de Hill) :
C17H20N2S · HCl
Numéro CAS:
58-33-3
Poids moléculaire :
320.88
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750972
MDL number:
MFCD00012652
Beilstein/REAXYS Number:
4166397

Principaux documents

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InChI

1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H

SMILES string

Cl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C

InChI key

XXPDBLUZJRXNNZ-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

promethazine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

Gene Information

human ... HRH1(3269)

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Catégories apparentées

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Promethazine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1

Classe de stockage

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Mario Schietroma et al.
Journal of the American College of Surgeons, 220(5), 921-933 (2015-04-05)
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. An independent statistical analysis based on the summary data tables and statistical results reported in the
Cheryl C Y Loh et al.
PloS one, 9(10), e110800-e110800 (2014-10-25)
Chloroquine was a cheap, extremely effective drug against Plasmodium falciparum until resistance arose. One approach to reversing resistance is the inhibition of chloroquine efflux from its site of action, the parasite digestive vacuole. Chloroquine accumulation studies have traditionally relied on
Shigeru Hishinuma et al.
Biochemical pharmacology, 91(2), 231-241 (2014-07-30)
Differential binding sites for first- and second-generation antihistamines were indicated on the basis of the crystal structure of human histamine H1 receptors. In this study, we evaluated differences between the thermodynamic driving forces of first- and second-generation antihistamines for human
Jung Yeon Kim et al.
Biomedical chromatography : BMC, 29(3), 465-474 (2014-08-01)
The purpose of this study was to develop and validate an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistamines (illegal additives) in dietary supplements. The limits of detection and quantitation of the method ranged from 1.5 to 2.5
Andrew Curtright et al.
PloS one, 10(1), e0116766-e0116766 (2015-01-15)
Acute and chronic pain conditions are often debilitating, inflicting severe physiological, emotional and economic costs and affect a large percentage of the global population. However, the development of therapeutic analgesic agents based primarily on targeted drug development has been largely

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