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A propos de cet article
Formule empirique (notation de Hill) :
C3H7NO
Numéro CAS:
Poids moléculaire :
73.09
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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Laissez-nous vous aiderNom du produit
Residual Solvent Class 2 - N,N-Dimethylformamide, United States Pharmacopeia (USP) Reference Standard
SMILES string
N(C)(C)C=O
InChI
1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
InChI key
ZMXDDKWLCZADIW-UHFFFAOYSA-N
grade
pharmaceutical primary standard
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Residual Solvent Class 2 - N,N-Dimethylformamide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
General description
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
Classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
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K Tanaka et al.
Sangyo igaku. Japanese journal of industrial health, 24(1), 3-12 (1982-01-01)
Industrial use of N, N-dimethylformamide (DMF) is increasing in recent years. The toxic properties of this substance are reviewed from the standpoint of industrial hygiene. Hepatotoxicity has been emphasized by many authors. Care should be taken against the skin absorption
Shengtao Ding et al.
Angewandte Chemie (International ed. in English), 51(37), 9226-9237 (2012-08-30)
Often used as a common solvent for chemical reations and utilized widely in industry as a reagent, N,N-dimethylformamide (DMF) has played an important role in organic synthesis for a long time. Numerous highly useful articles and reviews discussing its utilizations
Metabolism of N,N-dimethylformamide: key to the understanding of its toxicity.
A Gescher
Chemical research in toxicology, 6(3), 245-251 (1993-05-01)
Cui Wang et al.
Environmental pollution (Barking, Essex : 1987), 190, 133-138 (2014-04-22)
Occupational and experimental studies have revealed the organs most affected by dimethylformamide (DMF) are liver and gastrointestinal tract. However, few studies have focused on the potential effect of outdoor pollution of DMF. This study examined the health risk of hospitalization
Xiaowen Xu et al.
Organic letters, 16(13), 3540-3543 (2014-06-17)
A novel straightforward synthesis of both symmetrical and unsymmetrical 2,4-disubstituted-1,3,5-triazines via aerobic copper-catalyzed cyclization of amidines with DMF as a one-carbon synthon has been developed. The presented method allows synthesizing the products that are currently inaccessible or challenging to prepare
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