Agonist
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239824 Sigma-AldrichCXCR7 Agonist, VUF11207 - CAS 1378524-41-4 - Calbiochem - (CXCR7 Agonist, VUF11207 - CAS 1378524-41-4 - Calbiochem)
CXCR7 Agonist, VUF11207, CAS 1378524-41-4, is a high affinity and high potency ligand of CXCR7 (pKi = 8.1). Induces the recruitment of β-arrestin2 and subsequent interenalization of CXCR7.
182690 Sigma-AldrichAhR Agonist V, VAF347 - CAS 574759-62-9 - Calbiochem - (AhR Agonist V, VAF347 - CAS 574759-62-9 - Calbiochem)
The AhR Agonist V, VAF347 controls the biological activity of AhR. This small molecule/inhibitor is primarily used for Biochemicals applications.
530409 Sigma-AldrichTLR8 Agonist, cpd14b - CAS 1607440-08-3 - Calbiochem - (TLR8 Agonist, cpd14b - CAS 1607440-08-3 - Calbiochem)
A potent agonist of Toll-like receptor 8 agonist (TLR8, EC₅₀ = 200 nM).
530533 Sigma-AldrichTRPV4 Agonist, GSK1016790A - CAS 942206-85-1 - Calbiochem - (TRPV4 Agonist, GSK1016790A - CAS 942206-85-1 - Calbiochem)
A cell-permeable, potent, selective agonist of TRPV4 channel. Enhances Ca2+ flux in a variety of human and mouse cells (EC₅₀ = 2.1 nM for human TRPV4).
681664 Sigma-AldrichWnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem - (Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem)
The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
508578 Sigma-AldrichTSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem - (TSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem)
A 4'-chloro derivative of diazepam that lacks affinity for GABA-A receptors, but can serve as a ligand for the peripheral benzodiazepine receptor.
681665 Sigma-AldrichWnt Agonist - CAS 853220-52-7 - Calbiochem - (Wnt Agonist - CAS 853220-52-7 - Calbiochem)
Wnt Agonist, CAS 853220-52-7, is a cell-permeable, potent, and selective activator of Wnt signaling. Does not inhibit the activity of GSK-3β (IC50 greater than 60 µM).
681667 Sigma-AldrichWnt Agonist II, SKL2001 - CAS 909089-13-0 - Calbiochem - (Wnt Agonist II, SKL2001 - CAS 909089-13-0 - Calbiochem)
Wnt Agonist II, SKL2001, CAS 909089-13-0, upregulates β-catenin-regulated transcription by disrupting β-catenin & Axin interaction. Prevents β-catenin phosphorylation and proteasomal degradation.
