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Merck

38800

Malachite Green chloride

analytical standard

Synonym(s):

N,N,N′,N′-Tetramethyl-4,4′-diaminotriphenylcarbenium chloride, Basic Green 4, Malachite Green

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About This Item

Empirical Formula (Hill Notation):
C23H25ClN2
CAS Number:
569-64-2
Molecular Weight:
364.91
EC Number:
209-322-8
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329755786
MDL number:
MFCD00011751
Colour Index Number:
42000
Beilstein/REAXYS Number:
3580148

Product Name

Malachite Green chloride, analytical standard

InChI key

FDZZZRQASAIRJF-UHFFFAOYSA-M

InChI

1S/C23H25N2.ClH/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4;/h5-17H,1-4H3;1H/q+1;/p-1

SMILES string

[Cl-].CN(C)c1ccc(cc1)C(\c2ccccc2)=C3\C=CC(\C=C3)=[N+](\C)C

grade

analytical standard

assay

≥90% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

Quality Level

100

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Application

Malachite Green chloride may be used as an analytical standard to investigate its carcinogenic nature in the animal matrix. The techniques, proton nuclear magnetic resonance (1H), carbon-13 nuclear magnetic resonance (13C NMR), high-performance liquid chromatography (HPLC), and gas chromatography (GC) are used to confirm the identity of the material and to determine the purity of malachite green chloride.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Malachite Green chloride (MG), a neat reference standard, is provided for the analyte detection, food color quality, and safety control of your products! Malachite Green is a low-cost, highly efficient, cationic triphenylmethane dye with high efficacy for treating fungal, bacterial, and parasitic infections. MG is also employed in paper, textile, acrylic industries, and as an anthelmintic agent, food and color additive, medical disinfectant, etc.
Malachite green chloride is a triphenylmethane dye, which generally can find applications in aquaculture and highly effective against fungal infections.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM8761
BCCJ8480
BCCD5864

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Carcinogenicity of malachite green chloride and leucomalachite green in B6C3F1 mice and F344 rats
Culp JS, et al.
Food And Chemical Toxicology, 44(8), 1204-1212 (2006)
Effects of malachite green (MG) and its major metabolite, leucomalachite green (LMG), in two human cell lines
Stammati A, et al.
Toxicology in vitro, 19(7), 853-858 (2005)
Crystall M D Swarbrick et al.
Nucleic acids research, 45(22), 12904-12920 (2017-11-23)
The protein-RNA interactions within the flavivirus replication complex (RC) are not fully understood. Our structure of dengue virus NS3 adenosine triphosphatase (ATPase)/helicase bound to the conserved 5' genomic RNA 5'-AGUUGUUAGUCU-3' reveals that D290 and R538 make specific interactions with G2
Effects of malachite green (MG) and its major metabolite, leucomalachite green (LMG), in two human cell lines
Stammati A,et al.
Toxicology in vitro, 19, 853-858 (2005)
Determination of malachite green in aquatic products based on magnetic molecularly imprinted polymers
Lin Z-Z, et al.
Food Chemistry, 200, 32-37 (2016)
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