H9627

Hematoxylin

Name: Hematoxylin
Brand: SIGMA

Synonym(s):

Natural Black 1

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All Photos(1)

About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₄O₆ · xH₂O

CAS Number:

517-28-2

Molecular Weight:

302.28 (anhydrous basis)

EC Number:

208-237-3

UNSPSC Code:

12352204

NACRES:

NA.32

PubChem Substance ID:

57654281

MDL number:

MFCD00078111

Colour Index Number:

75290

Beilstein/REAXYS Number:

91400

InChI key

WZUVPPKBWHMQCE-XJKSGUPXSA-N

InChI

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1

SMILES string

Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O

form

powder

technique(s)

titration: suitable

mp

200 °C (dec.) (lit.)

solubility

95% ethanol: 1 mg/mL

Quality Level

200

Gene Information

rat ... Adora1(29290), Adora2a(25369)

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Related Categories

Analytical Reagents

Indicators

Application

Hematoxylin has been used for staining gastric cancer tissues, myocardial tissue, heart sections and ovarian nuclei.

Biochem/physiol Actions

Hematoxylin is an organic stain which chelates with metal ions and binds to DNA and RNA. It is used for staining nucleus of the cells. Hematoxylin along with eosin stain is used in the diagnosis of invasion stage in tumors.

pictograms

GHS07

signalword

Warning

hcodes

H319

pcodes

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Down-regulation of miR-327 alleviates ischemia/reperfusion-induced myocardial damage by targeting RP105

Yang Y, et al.

Cellular Physiology and Biochemistry, 49(3), 1049-1063 (2018)

Hematoxylin and eosin staining of intact tissues via delipidation and ultrasound

Li Y, et al.

Scientific Reports, 8(1), 12259-12259 (2018)

In Situ Molecular Pathology and Co-Expression Analyses, 81-131 (2013)

Clinical significance and effect of Sam68 expression in gastric cancer

Xiao J, et al.

Oncology Letters, 15(4), 4745-4752 (2018)

A novel human S10F-Hsp20 mutation induces lethal peripartum cardiomyopathy

Liu GS, et al.

Journal of Cellular and Molecular Medicine (2018)

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