USP

Foscarnet sodium

Name: Foscarnet sodium
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Sodium phosphonoformate tribasic hexahydrate, Foscarnet, Phosphonoformic acid trisodium salt hexahydrate

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About This Item

Linear Formula:

Na₂O₃PCO₂Na · 6H₂O

CAS Number:

34156-56-4

Molecular Weight:

300.04

NACRES:

NA.24

PubChem Substance ID:

329749891

UNSPSC Code:

41116107

MDL number:

MFCD00150176

Product Name

Foscarnet sodium, United States Pharmacopeia (USP) Reference Standard

InChI key

ILRVASBWNRYBFD-UHFFFAOYSA-K

SMILES string

O.O.O.O.O.O.[Na+].[Na+].[Na+].[O-]C(=O)P([O-])([O-])=O

InChI

1S/CH3O5P.3Na.6H2O/c2-1(3)7(4,5)6;;;;;;;;;/h(H,2,3)(H2,4,5,6);;;;6*1H2/q;3*+1;;;;;;/p-3

grade

pharmaceutical primary standard

API family

foscarnet

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Analytical Reference Materials for Pharma QC

Pharmacopeia & Metrological Institute Standards

Reference Materials

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Application

Foscarnet sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

GHS08

signalword

Warning

hcodes

H341,H373

pcodes

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Muta. 2 - STOT RE 2

target_organs

Kidney,Bone

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility.

Jocelyne Piret et al.

Journal of virology, 89(8), 4636-4644 (2015-02-13)

DNA polymerases of the Herpesviridae and bacteriophage RB69 belong to the α-like DNA polymerase family. In spite of similarities in structure and function, the RB69 enzyme is relatively resistant to foscarnet, requiring the mutation V478W in helix N to promote

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