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About This Item
Empirical Formula (Hill Notation):
C14H22ClN3O2 · HCl · H2O
CAS Number:
Molecular Weight:
354.27
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
Product Name
Metoclopramide hydrochloride, United States Pharmacopeia (USP) Reference Standard
SMILES string
[Cl-].Clc1c(cc(c(c1)C(=O)NCCN(CC)CC)OC)N.O.[H+]
InChI
1S/C14H22ClN3O2.ClH.H2O/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H;1H2
InChI key
KJBLQGHJOCAOJP-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
metoclopramide
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Metoclopramide hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
Also, for use with USP monographs such as:
- Metoclopramide Tablets
- Metoclopramide Oral Solution
- Metoclopramide Injection
- Prazosin Hydrochloride
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Moshe Yair Kasirer et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(5), G439-G444 (2014-01-11)
Feeding intolerance resulting from delayed gastric emptying is common in premature neonates. Metoclopramide (MCP), the most frequently used prokinetic drug in neonates, enhances gastric muscle contractility through inhibition of dopamine receptors. Although its therapeutic benefit is established in adults, limited
Xiong Wang et al.
African journal of traditional, complementary, and alternative medicines : AJTCAM, 10(4), 24-35 (2013-10-23)
The study investigated the pharmacodynamism and mechanism of Chinese medicinal formula-Huiru Yizeng Yihao (NO.1 HRYZ) on the model rats of hyperpro-lactinemia and the model rats of hyperplasia of mammary gland (HMG), and studied the internal connection between hyperprolactinemia and HMG..
Z Eras et al.
European review for medical and pharmacological sciences, 17(12), 1655-1657 (2013-07-09)
Gastroesophageal reflux disease (GERD) may occur with poor weight gain, esophagitis, hematemesis and respiratory problems in an infant. Common treatment strategies include positioning, feeding thickeness, histamine2 receptor antagonists, antiacids, and prokinetics. Metoclopramide is a prokinetic drug used to treat GERD
Allen Lee
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 17(9), 1553-1556 (2013-06-27)
Gastroparesis is a chronic motility disorder that leads to delayed gastric emptying and negatively impacts morbidity, mortality, and quality of life. This paper provides an overview of the pathophysiology leading to symptoms in gastroparesis, discusses tests for diagnosis, and examines
Radwa A Mohamed et al.
The Journal of pharmacy and pharmacology, 65(11), 1607-1621 (2013-10-10)
The purpose of this study was to formulate and characterize metoclopramide solid lipid nanoparticles (MCP-SLNs) and incorporating it into suppository bases for treatment of nausea and vomiting, produced with chemotherapeutic agents, using one dose per day. MCP-SLNs was prepared using
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