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Merck

1526200

USP

Phenoxyethanol

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-Phenoxyethanol, Ethylene glycol monophenyl ether, Phenylglycol

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About This Item

Linear Formula:
C6H5OCH2CH2OH
CAS Number:
122-99-6
Molecular Weight:
138.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750804
MDL number:
MFCD00002857
Beilstein/REAXYS Number:
1364011

Product Name

Phenoxyethanol, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H2

SMILES string

OCCOc1ccccc1

InChI key

QCDWFXQBSFUVSP-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

phenoxyethanol

manufacturer/tradename

USP

bp

244-246 °C

mp

11-13 °C

density

1.107 g/mL at 20 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Phenoxyethanol USP reference standard for use in specified quality tests and assays.Also used to prepare standard stock solution for impurity analysis by Gas Chromatography in conjunction with Flame ionization detector in Phenoxyethanol according to United States Pharmacopeia (USP) monograph.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

signalword

Danger

pictograms

CorrosionExclamation mark
GHS05,GHS07

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

258.8 °F - closed cup

flash_point_c

126 °C - closed cup

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Phenoxyethanol
United States Pharmacopeia, 5869-5869 (2020)
J Scognamiglio et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50 Suppl 2, S244-S255 (2011-11-01)
A toxicologic and dermatologic review of 2-phenoxyethanol when used as a fragrance ingredient is presented. 2-Phenoxyethanol is a member of the fragrance structural group Aryl Alkyl Alcohols and is a primary alcohol. The AAAs are a structurally diverse class of
Angela E Aakhus et al.
Dermatitis : contact, atopic, occupational, drug, 22(3), 127-140 (2011-05-17)
Methyldibromoglutaronitrile/phenoxyethanol (Euxyl K 400) is a preservative found in both personal care products and industrial sources. Although Euxyl K 400 initially appeared to have low sensitizing potential, increased prevalence of contact allergy to Euxyl K 400 led to regulatory intervention.
T W Chew et al.
Oncogene, 33(21), 2717-2727 (2013-07-03)
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell growth and tissue development through their distinct signaling pathways. Although much has been learnt about their individual functions in both cell and animal models, the physiological

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